🔬 Introduction
Ceftibid-100 DT Tablet is a third-generation cephalosporin antibiotic used to treat a wide range of bacterial infections. Designed as a dispersible tablet, it provides easy administration for both children and adults, ensuring rapid absorption and maximum effectiveness.
⚕️ Pharmacokinetics & Bioavailability
✔ Absorption: Well absorbed from the gastrointestinal tract
✔ Bioavailability: ~40–50% (not affected by food)
✔ Peak Plasma Concentration: 2–4 hours after administration
✔ Protein Binding: ~65%
✔ Half-life: ~3–4 hours (longer in renal impairment)
✔ Excretion: Primarily in urine (50%) and feces (10%)
🦠 Indications & Uses
🚑 Ceftibid-100 DT Tablet is prescribed for:
✔ Respiratory Tract Infections (Tonsillitis, Pharyngitis, Bronchitis, Pneumonia)
✔ Otitis Media (Middle Ear Infection)
✔ Urinary Tract Infections (UTI) (Cystitis, Pyelonephritis)
✔ Gastrointestinal Infections (Typhoid Fever, Bacterial Diarrhea)
✔ Skin & Soft Tissue Infections (Impetigo, Cellulitis)
💊 Dosage & Administration
✔ Children (6 months – 12 years): 8 mg/kg/day (once daily or divided into two doses)
✔ Adults & Adolescents (>12 years or >45 kg): 200-400 mg once daily or in divided doses
📌 How to take:
- Disperse the tablet in a small amount of water before consumption.
- Can be taken with or without food.
⚙️ Mechanism of Action
✔ Inhibits bacterial cell wall synthesis, leading to bacterial lysis and death
✔ Bactericidal action (kills bacteria directly)
✔ Effective Against: Streptococcus, Haemophilus influenzae, Escherichia coli, Salmonella, Klebsiella, Proteus
⚠️ Warnings & Precautions
❌ Penicillin Allergy: Cross-sensitivity with cephalosporins may occur
❌ Renal Impairment: Dose adjustment required in severe cases
❌ Clostridium difficile Infection: Risk of antibiotic-associated diarrhea
❌ Superinfection Risk: Prolonged use may lead to fungal or resistant bacterial infections
🚨 Adverse Effects
✔ Common: Nausea, vomiting, diarrhea, abdominal pain, headache
✔ Serious: Allergic reactions, liver enzyme elevation, pseudomembranous colitis
⚡ Drug Interactions
⚡ Antacids (Containing Magnesium/Aluminum): Reduce cefixime absorption
⚡ Probenecid: Increases cefixime levels, prolonging its effect
⚡ Warfarin & Anticoagulants: Increases bleeding risk
⚡ Live Vaccines (e.g., Typhoid Vaccine): May reduce vaccine efficacy
📦 Storage Conditions
📌 Store in a cool, dry place below 25°C
📌 Keep out of reach of children
🏆 Conclusion
Ceftibid-100 DT Tablet (Cefixime 100 mg) is a trusted and effective antibiotic for treating bacterial infections. With its dispersible formulation, it ensures easy intake and quick relief.
✅ Trusted Pharmaceutical Company in India
Since 2007, we have been at the forefront of scientific research and development, consistently delivering breakthrough medicines and therapies that address critical medical challenges. Our experienced team of experts works tirelessly to ensure that our products meet the highest standards of efficacy, safety, and compliance.
🚀 Ceftibid-100 DT – Powerful Antibiotic for Effective Infection Control! 💊💪
📞 Contact Us
📞 Phone: +91-9845329972
📧 Email: info@minovalifesciences.com
🌐 Website: Minova Life Sciences