🔬 Introduction
Ceftibid-50 Dry Syrup is a third-generation cephalosporin antibiotic specially formulated for pediatric patients. It provides broad-spectrum bacterial coverage, making it highly effective in treating respiratory, urinary, and gastrointestinal infections. Its excellent taste and easy dosing ensure better compliance in children.
⚕️ Pharmacokinetics & Bioavailability
✔ Absorption: Well absorbed in the gastrointestinal tract
✔ Bioavailability: ~40–50% (not affected by food)
✔ Peak Plasma Concentration: 2–4 hours after administration
✔ Protein Binding: ~65%
✔ Half-life: ~3–4 hours (longer in renal impairment)
✔ Excretion: Primarily in urine (50%) and feces (10%)
🦠 Indications & Uses
🚑 Ceftibid-50 Dry Syrup is prescribed for:
✔ Respiratory Tract Infections (Tonsillitis, Pharyngitis, Bronchitis, Pneumonia)
✔ Otitis Media (Middle Ear Infection)
✔ Urinary Tract Infections (UTI) (Cystitis, Pyelonephritis)
✔ Gastrointestinal Infections (Typhoid Fever, Bacterial Diarrhea)
✔ Skin & Soft Tissue Infections (Impetigo, Cellulitis)
💊 Dosage & Administration
Children (Based on Body Weight):
✔ Standard Dose: 8 mg/kg once daily OR 4 mg/kg twice daily for 7–14 days
Weight | Dose (Once Daily) | Dose (Twice Daily) |
5-9 kg | 2.5 mL | 1.25 mL |
10-19 kg | 5 mL | 2.5 mL |
20-29 kg | 7.5 mL | 3.75 mL |
30-40 kg | 10 mL | 5 mL |
📌 Administration: Shake well before use. Can be taken with or without food.
⚙️ Mechanism of Action
✔ Inhibits bacterial cell wall synthesis, leading to bacterial lysis and death
✔ Bactericidal action (kills bacteria directly)
✔ Effective Against: Streptococcus, Haemophilus influenzae, Escherichia coli, Salmonella, Klebsiella, Proteus
⚠️ Warnings & Precautions
❌ Penicillin Allergy: Cross-sensitivity with cephalosporins may occur
❌ Renal Impairment: Dose adjustment required in severe cases
❌ Clostridium difficile Infection: Risk of antibiotic-associated diarrhea
❌ Superinfection Risk: Prolonged use may lead to fungal or resistant bacterial infections
🚨 Adverse Effects
✔ Common: Nausea, vomiting, diarrhea, abdominal pain, headache
✔ Serious: Allergic reactions, liver enzyme elevation, pseudomembranous colitis
⚡ Drug Interactions
⚡ Antacids (Containing Magnesium/Aluminum): Reduce cefixime absorption
⚡ Probenecid: Increases cefixime levels, prolonging its effect
⚡ Warfarin & Anticoagulants: Increases bleeding risk
⚡ Live Vaccines (e.g., Typhoid Vaccine): May reduce vaccine efficacy
📦 Storage Conditions
📌 Store in a cool, dry place below 25°C
📌 After reconstitution, use within 7 days (keep refrigerated)
📌 Keep out of reach of children
🏆 Conclusion
Ceftibid-50 Dry Syrup (Cefixime 50 mg/5 mL) is a trusted antibiotic for treating bacterial infections in children. Its broad-spectrum action, pleasant taste, and effective formulation make it a preferred choice among pediatricians.
✅ Trusted Pharmaceutical Company in India
Since 2007, we have been at the forefront of scientific research and development, consistently delivering breakthrough medicines and therapies that address critical medical challenges. Our experienced team of experts works tirelessly to ensure that our products meet the highest standards of efficacy, safety, and compliance.
💊 🚀 Ceftibid-50 – Superior Protection Against Pediatric Infections! 💪✨
📞 Contact Us
📞 Phone: +91-9845329972
📧 Email: info@minovalifesciences.com
🌐 Website: Minova Life Sciences
