🔬 Introduction
Ceftibid-100 Dry Syrup is a third-generation cephalosporin antibiotic designed to treat pediatric bacterial infections. It is highly effective against a broad range of respiratory, urinary, and gastrointestinal infections. With its pleasant taste and once-daily dosing, it ensures better compliance in children.
⚕️ Pharmacokinetics & Bioavailability
✔ Absorption: Well absorbed from the gastrointestinal tract
✔ Bioavailability: ~40–50% (not affected by food)
✔ Peak Plasma Concentration: 2–4 hours after administration
✔ Protein Binding: ~65%
✔ Half-life: ~3–4 hours (longer in renal impairment)
✔ Excretion: Primarily in urine (50%) and feces (10%)
🦠 Indications & Uses
🚑 Ceftibid-100 Dry Syrup is prescribed for treating:
✔ Respiratory Tract Infections (Tonsillitis, Pharyngitis, Bronchitis, Pneumonia)
✔ Otitis Media (Middle Ear Infection)
✔ Urinary Tract Infections (UTI) (Cystitis, Pyelonephritis)
✔ Gastrointestinal Infections (Typhoid Fever, Bacterial Diarrhea)
✔ Skin & Soft Tissue Infections (Impetigo, Cellulitis)
💊 Dosage & Administration
Children (Based on Body Weight):
✔ Standard Dose: 8 mg/kg once daily OR 4 mg/kg twice daily for 7–14 days
|
Weight |
Dose (Once Daily) |
Dose (Twice Daily) |
|
5-9 kg |
2.5 mL |
1.25 mL |
|
10-19 kg |
5 mL |
2.5 mL |
|
20-29 kg |
7.5 mL |
3.75 mL |
|
30-40 kg |
10 mL |
5 mL |
📌 Administration: Shake well before use. Can be taken with or without food.
⚙️ Mechanism of Action
✔ Inhibits bacterial cell wall synthesis, leading to bacterial lysis and death
✔ Bactericidal action (kills bacteria directly)
✔ Effective Against: Streptococcus, Haemophilus influenzae, Escherichia coli, Salmonella, Klebsiella, Proteus
⚠️ Warnings & Precautions
❌ Penicillin Allergy: Cross-sensitivity with cephalosporins may occur
❌ Renal Impairment: Dose adjustment required in severe cases
❌ Clostridium difficile Infection: Risk of antibiotic-associated diarrhea
❌ Superinfection Risk: Prolonged use may lead to fungal or resistant bacterial infections
🚨 Adverse Effects
✔ Common: Nausea, vomiting, diarrhea, abdominal pain, headache
✔ Serious: Allergic reactions, liver enzyme elevation, pseudomembranous colitis
⚡ Drug Interactions
⚡ Antacids (Containing Magnesium/Aluminum): Reduce cefixime absorption
⚡ Probenecid: Increases cefixime levels, prolonging its effect
⚡ Warfarin & Anticoagulants: Increases bleeding risk
⚡ Live Vaccines (e.g., Typhoid Vaccine): May reduce vaccine efficacy
📦 Storage Conditions
📌 Store in a cool, dry place below 25°C
📌 After reconstitution, use within 7 days (keep refrigerated)
📌 Keep out of reach of children
🏆 Conclusion
Ceftibid-100 Dry Syrup (Cefixime 100 mg/5 mL) is a highly effective, well-tolerated antibiotic for pediatric bacterial infections. Its broad-spectrum coverage, excellent taste, and easy dosing make it a preferred choice for children.
✅ Trusted Pharmaceutical Company in India
Since 2007, we have been at the forefront of scientific research and development, consistently delivering breakthrough medicines and therapies that address critical medical challenges. Our experienced team of experts works tirelessly to ensure that our products meet the highest standards of efficacy, safety, and compliance.
💊Ceftibid-100 – Advanced Antibiotic Protection for Pediatric Infections! 💪
📞 Contact Us
📞 Phone: +91-9845329972
📧 Email: info@minovalifesciences.com
🌐 Website: Minova Life Sciences
