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Minoclav – 1.2G Injection

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🔬 Introduction

Minoclav – 1.2G Injection is a broad-spectrum intravenous antibiotic designed for the treatment of severe bacterial infections. With Amoxycillin, a beta-lactam antibiotic, and Clavulanic Acid, a beta-lactamase inhibitor, it effectively combats antibiotic-resistant infections. This combination is commonly used in hospital settings for critically ill patients requiring intravenous (IV) administration.

⚕️ Pharmacokinetics & Bioavailability

✔ Amoxycillin Bioavailability: ~85% (IV)
✔ Peak Plasma Concentration: Within 30-60 minutes after IV administration
✔ Protein Binding: ~17-20%
✔ Half-life: ~1-1.5 hours
✔ Excretion: Primarily via urine (~60-70%)

✔ Clavulanic Acid: Enhances Amoxycillin’s efficacy by inhibiting beta-lactamase enzymes, preventing bacterial resistance

🦠 Indications & Uses

🚑 Minoclav – 1.2G Injection is used for treating moderate to severe infections, including:

✔ Severe Respiratory Tract Infections – Pneumonia, Severe Bronchitis
✔ Complicated Urinary Tract Infections (UTIs) – Pyelonephritis
✔ Severe Skin & Soft Tissue Infections – Cellulitis, Abscesses
✔ Complicated Intra-Abdominal Infections – Peritonitis
✔ Bone & Joint Infections – Osteomyelitis
✔ Severe ENT Infections – Sinusitis, Otitis Media
✔ Gynecological Infections – Pelvic Inflammatory Disease
✔ Septicemia & Post-Surgical Infections

💉 Dosage & Administration

✔ Route: Intravenous (IV) administration only
✔ Dosage: As per physician’s guidance based on infection severity

📌 Administration Guidelines:

  • Given as a slow IV infusion over 30-40 minutes
  • Reconstitute with sterile water for Injection
  • Ensure complete dosage regimen to prevent antibiotic resistance

⚙️ Mechanism of Action

✔ Amoxycillin: Inhibits bacterial cell wall synthesis, causing bacterial death (bactericidal action)
✔ Clavulanic Acid: Blocks beta-lactamase enzymes, preventing bacterial resistance
✔ Effective Against: Gram-positive and Gram-negative bacteria, including Staphylococcus, Streptococcus, Escherichia coli, Klebsiella, Haemophilus influenzae, and more

⚠️ Warnings & Precautions

❌ Allergy Alert: Avoid in patients allergic to penicillins or cephalosporins
❌ Renal Impairment: Dose adjustment required for patients with kidney disease
❌ Superinfection Risk: Prolonged use may lead to secondary infections

🚨 Adverse Effects

✔ Common: Nausea, vomiting, mild diarrhea, local pain at Injection site
✔ Serious (Rare): Severe allergic reactions (anaphylaxis), liver enzyme elevation

⚡ Drug Interactions

⚡ Probenecid: Increases Amoxycillin levels in the blood
⚡ Methotrexate: Increased toxicity risk
⚡ Anticoagulants (Warfarin): May prolong bleeding time

📦 Storage Conditions

📌 Store in a cool, dry place below 25°C
📌 Use immediately after reconstitution
📌 Protect from light and moisture

🏆 Conclusion

Minoclav – 1.2G Injection is a potent IV antibiotic designed for hospital-based treatment of severe infections. With broad-spectrum coverage and enhanced bacterial resistance control, it is a trusted choice in critical care settings.

✅ Trusted Pharmaceutical Company in India

Since 2007, we have been at the forefront of scientific research and development, consistently delivering breakthrough medicines and therapies that address critical medical challenges. Our experienced team of experts works tirelessly to ensure that our products meet the highest standards of efficacy, safety, and compliance.

🚀 Minoclav – 1.2G Injection – Powerful IV Protection Against Resistant Infections! 💊💪📞 Contact Us

📞 Phone: +91-9845329972
📧 Email: info@minovalifesciences.com
🌐 Website: Minova Life Sciences

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