🔬 Introduction
ZEFURO – 500 Tablets is a broad-spectrum cephalosporin antibiotic designed to combat mild to severe bacterial infections. It provides high bioavailability and excellent penetration into tissues, making it a trusted choice for respiratory, urinary, skin, and soft tissue infections.
⚕️ Pharmacokinetics & Bioavailability
✔ Bioavailability: 40-50% (Enhanced with Food)
✔ Half-life: 1.2–1.6 hours
✔ Metabolism: Liver (Prodrug Activation)
✔ Excretion: Renal (Unchanged Form)
🦠 Indications & Uses
🚑 ZEFURO – 500 Tablets is used for the treatment of:
✔ Respiratory Tract Infections – Pneumonia, Bronchitis, Tonsillitis
✔ Urinary Tract Infections (UTIs) – Cystitis, Pyelonephritis
✔ Skin & Soft Tissue Infections – Cellulitis, Abscesses, Impetigo
✔ Ear, Nose & Throat (ENT) Infections – Sinusitis, Otitis Media, Pharyngitis
✔ Bone & Joint Infections – Osteomyelitis
✔ Sexually Transmitted Infections (STIs) – Gonorrhea
💊 Dosage & Administration
✔ Route: Oral (Tablet)
✔ Recommended Dosage:
- Adults: 500 mg every 12 hours or as prescribed
- Children: Dose based on weight (Consult a physician)
📌 Administration Guidelines:
- Take with food for better absorption
- Do not crush or chew – swallow whole
- Complete full course to prevent resistance
⚙️ Mechanism of Action
✔ Cefuroxime Axetil (Cephalosporin):
- Inhibits bacterial cell wall synthesis
- Targets both Gram-positive & Gram-negative bacteria
- Bactericidal effect (Kills bacteria)
🔬 Effective Against:
- Streptococcus pneumoniae
- Haemophilus influenzae
- Escherichia coli (E. coli)
- Neisseria gonorrhoeae
⚠️ Warnings & Precautions
❌ Avoid in Penicillin-Allergic Patients (Cross-reactivity risk)
❌ Use with Caution in Kidney Disease
❌ Not for Use in Infants Under 3 Months
❌ Monitor for Clostridium difficile-Associated Diarrhea
🚨 Adverse Effects
✔ Common: Nausea, Vomiting, Diarrhea, Headache
✔ Serious (Rare): Anaphylaxis, Stevens-Johnson Syndrome, Liver Dysfunction
⚡ Drug Interactions
⚡ Antacids (Aluminum, Magnesium): Reduces absorption
⚡ Probenecid: Increases drug levels (Risk of toxicity)
⚡ Oral Contraceptives: May reduce contraceptive efficacy
📦 Storage Conditions
📌 Store in a cool, dry place below 30°C
📌 Protect from moisture & direct sunlight
📌 Keep out of reach of children
🏆 Conclusion
ZEFURO – 500 Tablets is a powerful cephalosporin antibiotic that provides broad-spectrum coverage against respiratory, urinary, and skin infections. With its enhanced absorption and effectiveness, it is a trusted choice for bacterial infections.
✅ Trusted Pharmaceutical Company in India
Since 2007, we have been at the forefront of scientific research and development, consistently delivering breakthrough medicines and therapies that address critical medical challenges. Our experienced team of experts works tirelessly to ensure that our products meet the highest standards of efficacy, safety, and compliance.
🚀 ZEFURO – 500 Tablets – Advanced Broad-Spectrum Protection Against Bacterial Infections! 💊✨
📞 Contact Us
📞 Phone: +91-9845329972
📧 Email: info@minovalifesciences.com
🌐 Website: Minova Life Sciences
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