Minova Life Science

ZEFURO – 500 Tablets

🔬 Introduction

ZEFURO – 500 Tablets is a broad-spectrum cephalosporin antibiotic designed to combat mild to severe bacterial infections. It provides high bioavailability and excellent penetration into tissues, making it a trusted choice for respiratory, urinary, skin, and soft tissue infections.

⚕️ Pharmacokinetics & Bioavailability

Bioavailability: 40-50% (Enhanced with Food)
Half-life: 1.2–1.6 hours
Metabolism: Liver (Prodrug Activation)
Excretion: Renal (Unchanged Form)

🦠 Indications & Uses

🚑 ZEFURO – 500 Tablets is used for the treatment of:

Respiratory Tract Infections – Pneumonia, Bronchitis, Tonsillitis
Urinary Tract Infections (UTIs) – Cystitis, Pyelonephritis
Skin & Soft Tissue Infections – Cellulitis, Abscesses, Impetigo
Ear, Nose & Throat (ENT) Infections – Sinusitis, Otitis Media, Pharyngitis
Bone & Joint Infections – Osteomyelitis
Sexually Transmitted Infections (STIs) – Gonorrhea

💊 Dosage & Administration

Route: Oral (Tablet)
Recommended Dosage:

  • Adults: 500 mg every 12 hours or as prescribed
  • Children: Dose based on weight (Consult a physician)

📌 Administration Guidelines:

  • Take with food for better absorption
  • Do not crush or chew – swallow whole
  • Complete full course to prevent resistance

⚙️ Mechanism of Action

Cefuroxime Axetil (Cephalosporin):

  • Inhibits bacterial cell wall synthesis
  • Targets both Gram-positive & Gram-negative bacteria
  • Bactericidal effect (Kills bacteria)

🔬 Effective Against:

  • Streptococcus pneumoniae
  • Haemophilus influenzae
  • Escherichia coli (E. coli)
  • Neisseria gonorrhoeae

⚠️ Warnings & Precautions

Avoid in Penicillin-Allergic Patients (Cross-reactivity risk)
Use with Caution in Kidney Disease
Not for Use in Infants Under 3 Months
Monitor for Clostridium difficile-Associated Diarrhea

🚨 Adverse Effects

Common: Nausea, Vomiting, Diarrhea, Headache
Serious (Rare): Anaphylaxis, Stevens-Johnson Syndrome, Liver Dysfunction

⚡ Drug Interactions

Antacids (Aluminum, Magnesium): Reduces absorption
Probenecid: Increases drug levels (Risk of toxicity)
Oral Contraceptives: May reduce contraceptive efficacy

📦 Storage Conditions

📌 Store in a cool, dry place below 30°C
📌 Protect from moisture & direct sunlight
📌 Keep out of reach of children

🏆 Conclusion

ZEFURO – 500 Tablets is a powerful cephalosporin antibiotic that provides broad-spectrum coverage against respiratory, urinary, and skin infections. With its enhanced absorption and effectiveness, it is a trusted choice for bacterial infections.

✅ Trusted Pharmaceutical Company in India

Since 2007, we have been at the forefront of scientific research and development, consistently delivering breakthrough medicines and therapies that address critical medical challenges. Our experienced team of experts works tirelessly to ensure that our products meet the highest standards of efficacy, safety, and compliance.

🚀 ZEFURO – 500 Tablets – Advanced Broad-Spectrum Protection Against Bacterial Infections! 💊✨

📞 Contact Us

📞 Phone: +91-9845329972
📧 Email: info@minovalifesciences.com
🌐 Website: Minova Life Sciences

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