•Exerts rapid pain relief compared with monotherapy in the management of acute painful OA flare-up’

•Superior tolerability and decreased side effects than diclofenac

•Most popular analgesic and anti inflammatory drugi used for the relief of Rheumatic & osteoarthritic pain

•Prevents worsening of arthritis by reducing IL-1 in polymorphonuclear cells.

•Significantly lowers incidence of adverse reaction as compared to meloxicam or rofecoxib.

• Provides more rapid improvement in knee flexion than piroxicam offers in 15 days of treatment.

 •Advantage of sustained release formulation provides patient compliance.