Minova Life Science

Minova life sciences - Pharmaceutical company

Minotob Eye Drops

COMPOSITION – Tobramycin Sulphate USP 0.3% + Benzalkonium Chloride Solution IP 0.04%


Tobramycin Sulphate + Benzalkonium chloride

Tobramycin Sulphate

  • Tobramycin is an aminoglycoside antibiotic marketed for topical ophthalmic use.
  • Due to tobramycin’s broad spectrum of activity, it has proven useful in controlling both superficial and deep infections of the eye and ocular adnexa (i.e., blepharitis, conjunctivitis, keratitis, and endophthalmitis).
  • Tobramycin is significantly more effective than gentamicin sulfate clinically, and the former exhibits a greater antibacterial efficacy, in the eye, against the combined conjunctival pathogens.

Benzalkonium chloride (Category III antiseptic)

  • Benzalkonium chloride (BAK), a quaternary ammonium salt, is the most common preservative used in eye drops.
  • Benzalkonium chloride is effective against both Gram-positive and Gram-negative bacteria as well as fungi. 
  • It may also act as a corneal penetration enhancer, leading to great ocular penetrance of active ingredients in BAK-preserved formulations. 

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