🔬 Introduction
Perocef – SB Injection is a potent broad-spectrum antibiotic that combines Cefoperazone (a third-generation cephalosporin) with Sulbactam (a β-lactamase inhibitor) to enhance effectiveness against resistant bacterial infections. This powerful combination ensures effective treatment of severe bacterial infections by overcoming antibiotic resistance.
⚕️ Pharmacokinetics & Bioavailability
✔ Cefoperazone Bioavailability: Administered intravenously or intramuscularly for rapid absorption
✔ Protein Binding: 82-93% (Cefoperazone)
✔ Half-life: 1.5 – 2 hours
✔ Excretion: Primarily via bile and urine
✔ Sulbactam Function: Inhibits β-lactamase enzymes, preventing bacterial resistance
🦠 Indications & Uses
🚑 Perocef – SB Injection is prescribed for:
✔ Respiratory Tract Infections – Pneumonia, Bronchitis
✔ Urinary Tract Infections (UTIs) – Pyelonephritis, Cystitis
✔ Skin & Soft Tissue Infections – Cellulitis, Abscesses
✔ Intra-Abdominal Infections – Peritonitis, Cholecystitis
✔ Gynecological Infections – Pelvic Inflammatory Disease (PID)
✔ Bone & Joint Infections – Osteomyelitis
✔ Septicemia & Bacteremia – Bloodstream Infections
💊 Dosage & Administration
✔ Route: Intravenous (IV) or Intramuscular (IM) injection
✔ Recommended Dosage: As per physician’s guidance based on infection severity and patient condition
📌 Administration Guidelines:
- For IV Use: Dilute in sterile water or compatible IV fluid and administer over 15-30 minutes
- For IM Use: Reconstitute with sterile water or lidocaine (to reduce pain) before injecting
- Complete the full course to prevent antibiotic resistance
⚙️ Mechanism of Action
✔ Cefoperazone: Inhibits bacterial cell wall synthesis, leading to bacterial death (bactericidal action)
✔ Sulbactam: Blocks β-lactamase enzymes, preventing bacterial resistance and enhancing Cefoperazone’s effectiveness
✔ Effective Against: Gram-positive and Gram-negative bacteria, including resistant strains
⚠️ Warnings & Precautions
❌ Allergy Alert: Avoid if allergic to cephalosporins or penicillins
❌ Liver & Kidney Disorders: Use with caution in patients with hepatic or renal impairment
❌ Bleeding Risk: Monitor patients on anticoagulants as Cefoperazone may prolong bleeding time
❌ Pregnancy & Breastfeeding: Use only if prescribed by a doctor
🚨 Adverse Effects
✔ Common: Diarrhea, nausea, vomiting, pain at injection site
✔ Serious (Rare): Allergic reactions, jaundice, blood clotting disorders
⚡ Drug Interactions
⚡ Aminoglycosides (Gentamicin, Amikacin): Increased nephrotoxicity risk
⚡ Oral Anticoagulants (Warfarin): May increase bleeding tendency
⚡ Alcohol: Avoid alcohol consumption as Cefoperazone may cause disulfiram-like reactions (flushing, nausea, vomiting)
📦 Storage Conditions
📌 Store in a cool, dry place below 25°C
📌 Protect from light and moisture
📌 Use reconstituted solution immediately for best efficacy
🏆 Conclusion
Perocef – SB Injection is a powerful combination therapy designed for severe bacterial infections, offering broad-spectrum coverage and enhanced efficacy. With the added protection of Sulbactam, it effectively combats resistant bacteria, making it a trusted choice for critical care infections.
✅ Trusted Pharmaceutical Company in India
Since 2007, we have been at the forefront of scientific research and development, consistently delivering breakthrough medicines and therapies that address critical medical challenges. Our experienced team of experts works tirelessly to ensure that our products meet the highest standards of efficacy, safety, and compliance.
🚀 Perocef – SB Injection – Dual Action for Superior Infection Control! 💉🔬
📞 Contact Us
📞 Phone: +91-9845329972
📧 Email: info@minovalifesciences.com
🌐 Website: Minova Life Sciences
