🔬 Introduction
Redinerv-N Tablets contain a combination of Pregabalin (75mg) and Nortriptyline (10mg), both of which work synergistically to treat neuropathic pain. These tablets are designed to alleviate the discomfort caused by conditions like diabetic neuropathy, post-herpetic neuralgia, and other forms of nerve-related pain.
⚕️ Pharmacokinetics & Bioavailability
Absorption: Rapid absorption from the gastrointestinal tract
Bioavailability: 90% for Pregabalin when taken orally
Half-life: Approximately 6 hours
Protein Binding: Pregabalin has low protein binding (around 0%)
Metabolism: Nortriptyline is metabolized in the liver
Excretion: Excreted primarily through the urine
🦠 Indications & Uses
Redinerv-N Tablets are primarily indicated for:
Neuropathic Pain Relief: Effective for treating nerve-related pain from diabetic neuropathy, post-herpetic neuralgia, and fibromyalgia.
Chronic Pain Management: Assists in managing chronic pain by acting on the nerve signals that trigger pain responses.
💊 Dosage & Administration
Adults & above 65:
Starting Dose: 75 mg once daily
Maintenance Dose: Can be increased to 150 mg/day if necessary, divided into two doses
Pediatric Patients (under 18 years):
Not recommended for children
Always follow your healthcare provider’s dosage instructions for optimal results.
⚙️ Mechanism of Action
Pregabalin works by binding to calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters and decreasing neuronal excitability.
Nortriptyline works by inhibiting the reuptake of serotonin and norepinephrine, which helps in modulating pain and improving mood.
⚠️ Warnings & Precautions
Liver Impairment: Use with caution if you have liver issues.
Kidney Dysfunction: Reduce the dosage in patients with renal impairment.
Pregnancy & Lactation: Should be used only if the potential benefit justifies the risk.
Drowsiness: May cause drowsiness or dizziness. Avoid driving or operating machinery until you understand how the drug affects you.
🚨 Adverse Effects
Common Side Effects: Drowsiness, dizziness, weight gain, and dry mouth.
Serious Side Effects: Suicidal thoughts, severe allergic reactions, and difficulty breathing. Immediate medical attention is needed if any serious side effects occur.
⚡ Drug Interactions
Central Nervous System Depressants: Increased risk of drowsiness and sedation when combined with alcohol or other CNS depressants.
Antihypertensive Drugs: Can enhance the hypotensive effect.
Antiepileptic Drugs: May require dosage adjustments.
📦 Storage Conditions
Store in a cool, dry place below 25°C.
Keep away from light and moisture.
Keep out of reach of children.
🏆 Conclusion
Redinerv-N Tablets combine Pregabalin and Nortriptyline to provide effective nerve pain relief. This combination is especially beneficial for people suffering from neuropathic pain, chronic pain conditions, and nerve disorders. It improves the quality of life by reducing discomfort and enhancing mobility.
Since 2007, Minova Life Sciences has been a leader in delivering innovative and effective medicines. With a commitment to the highest standards of research and manufacturing, we provide trusted solutions for critical medical challenges.
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Partner with Minova Life Sciences in our pharmaceutical franchise program to distribute high-quality products across India. Join us in offering life-changing medications to patients in need.
📞 Contact Us
Phone: +91-9845329972
Email: info@minovalifesciences.com
Website: Minova Life Sciences
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