🔬 Introduction
Quinolev-500 Tablets contain Levofloxacin, a broad-spectrum fluoroquinolone antibiotic that is highly effective in treating respiratory, urinary, skin, and gastrointestinal infections. It works by inhibiting bacterial DNA replication, leading to rapid bacterial eradication.
⚕️ Pharmacokinetics & Bioavailability
✔ Bioavailability: ~99% (Excellent oral absorption)
✔ Peak Plasma Concentration: Within 1-2 hours after administration
✔ Protein Binding: ~24-38%
✔ Half-life: ~6-8 hours
✔ Excretion: Primarily via urine (~87%)
🦠 Indications & Uses
🚑 Quinolev-500 Tablets are prescribed for:
✔ Respiratory Tract Infections (RTIs) – Pneumonia, Bronchitis, Sinusitis
✔ Urinary Tract Infections (UTIs) & Pyelonephritis
✔ Skin & Soft Tissue Infections
✔ Gastrointestinal Infections – Infectious Diarrhea, Typhoid Fever
✔ Sexually Transmitted Infections (STIs) – Gonorrhea
✔ Bone & Joint Infections
💊 Dosage & Administration
✔ Adult Dose: 500 mg once daily or as prescribed
✔ Severe Infections: 500 mg twice daily
✔ Pediatric Use: Not recommended in children under 18 years
✔ Route: Oral administration
📌 Administration Guidelines:
- Take with or without food
- Swallow whole with a glass of water
- Avoid excessive sun exposure during treatment
⚙️ Mechanism of Action
✔ Levofloxacin: Inhibits bacterial DNA gyrase and topoisomerase IV, preventing bacterial replication (bactericidal effect)
✔ Broad-Spectrum Action: Effective against E. coli, Klebsiella, Staphylococcus, Streptococcus, Pseudomonas
⚠️ Warnings & Precautions
❌ Tendon Rupture Risk: Increased risk in elderly patients
❌ QT Prolongation: Use cautiously in cardiac patients
❌ Photosensitivity: Avoid direct sunlight exposure
❌ Neuropathy & CNS Effects: May cause dizziness, headaches, or seizures
🚨 Adverse Effects
✔ Common: Nausea, vomiting, diarrhea, headache, dizziness
✔ Serious: Tendon rupture, seizures, liver dysfunction
⚡ Drug Interactions
⚡ Antacids (Magnesium/Aluminum): Reduce absorption of Levofloxacin
⚡ Blood Thinners (Warfarin): Increased bleeding risk
⚡ NSAIDs (Ibuprofen, Aspirin): May increase CNS side effects
📦 Storage Conditions
📌 Store in a cool, dry place below 30°C
📌 Keep away from direct sunlight and moisture
🏆 Conclusion
Quinolev-500 Tablets (Levofloxacin 500 mg) offer broad-spectrum antibacterial action, ensuring fast recovery from infections. With high oral bioavailability and once-daily dosing, it provides effective bacterial control with convenience.
✅ Trusted Pharmaceutical Company in India
Since 2007, we have been at the forefront of scientific research and development, consistently delivering breakthrough medicines and therapies that address critical medical challenges. Our experienced team of experts works tirelessly to ensure that our products meet the highest standards of efficacy, safety, and compliance.
🚀 Quinolev-500 – Powerful Fluoroquinolone for Effective Bacterial Control! 💊💪
📞 Contact Us
📞 Phone: +91-9845329972
📧 Email: info@minovalifesciences.com
🌐 Website: Minova Life Sciences
