Magaldrate

Drug Class: Antacid

• Magaldrate is an antacid that may be effective in preventing gastric damage caused by alcohol and anti-inflammatory drugs.

• Magaldrate did not affect gastric mucosal blood flow, but it increased gastric mucus secretion.

• It is demonstrated that the cyto-protective action of magaldrate on gastric mucosal cells which may be due to the protection of gastric mucosa from lipid peroxidation.

Simethicone

Drug Class: Gastrointestinal agents

• Simethicone is an orally administered antifoaming agent, used to reduce gas from the digestive tract in patients complaining of recurrent flatulence. 

• It is a mixture of dimethicone (polydimethylsiloxane) and hydrated silica gel (silicon dioxide). 

• It shows effect locally in the digestive tract and is not absorbed into the bloodstream. 

• Effective adjunct therapy in conditions where excessive gas is aggravating the symptoms in conditions such as dyspepsia, peptic ulcer, post-operative gaseous distention, irritable colon, etc.
• Aids in the elimination of gas from the digestive tract and reduces postoperative gas pains.