🔬 Introduction
Minoclav-LB 625 Tablets is an advanced broad-spectrum antibiotic designed to treat bacterial infections effectively while maintaining gut health. It combines Amoxycillin (a penicillin-class antibiotic) and Clavulanic Acid (a beta-lactamase inhibitor) with Lactic Acid Bacillus (a probiotic) to prevent antibiotic-associated diarrhea and restore the natural gut flora.
⚕️ Pharmacokinetics & Bioavailability
✔ Amoxycillin Bioavailability: ~75% (Rapid GI absorption)
✔ Clavulanic Acid Bioavailability: ~60%
✔ Lactic Acid Bacillus: Helps restore intestinal microflora, preventing diarrhea
✔ Peak Plasma Concentration: 1–2 hours after administration
✔ Protein Binding: Amoxycillin (~18%), Clavulanic Acid (~25%)
✔ Half-life: Amoxycillin (~1–1.5 hours), Clavulanic Acid (~1 hour)
✔ Excretion: Primarily in urine (~70% within 6 hours)
🦠 Indications & Uses
🚑 Minoclav-LB 625 Tablets is prescribed for:
✔ Respiratory Tract Infections (Bronchitis, Pneumonia, Tonsillitis, Sinusitis)
✔ Urinary Tract Infections (UTI) (Cystitis, Pyelonephritis)
✔ Skin & Soft Tissue Infections (Cellulitis, Wound Infections)
✔ Gastrointestinal Infections (Diarrhea, Bacterial Enteritis)
✔ Dental Infections (Abscesses, Periodontitis)
✔ Bone & Joint Infections
💊 Dosage & Administration
✔ Adults & Adolescents (>12 years): One tablet every 8-12 hours (as per physician’s guidance)
✔ Children (<12 years): Prefer pediatric suspension or as directed by a doctor
📌 How to take:
- Swallow the tablet whole with water.
- Take with or after food to reduce stomach discomfort and improve probiotic effectiveness.
⚙️ Mechanism of Action
✔ Amoxycillin: Inhibits bacterial cell wall synthesis, leading to bacterial death (bactericidal action)
✔ Clavulanic Acid: Prevents bacterial resistance by inhibiting beta-lactamase enzymes
✔ Lactic Acid Bacillus: Restores healthy gut bacteria, preventing diarrhea caused by antibiotics
✔ Effective Against: Streptococcus, Staphylococcus (non-MRSA), Haemophilus influenzae, Escherichia coli, Klebsiella, Proteus, Bacteroides
⚠️ Warnings & Precautions
❌ Penicillin Allergy: Avoid in patients with known hypersensitivity
❌ Liver Impairment: Use with caution in patients with hepatic disorders
❌ Kidney Impairment: Dose adjustment required in severe renal disease
❌ Clostridium difficile Infection: Risk of antibiotic-associated diarrhea
❌ Superinfection Risk: Prolonged use may lead to fungal or resistant bacterial infections
🚨 Adverse Effects
✔ Common: Nausea, vomiting, diarrhea, abdominal pain, skin rash
✔ Serious: Allergic reactions, liver enzyme elevation, Clostridium difficile infection
⚡ Drug Interactions
⚡ Allopurinol: Increases risk of skin rashes
⚡ Warfarin & Anticoagulants: May increase bleeding risk
⚡ Methotrexate: Increases toxicity risk
⚡ Probenecid: Delays amoxycillin excretion, prolonging its effect
⚡ Live Vaccines (e.g., Typhoid Vaccine): May reduce vaccine efficacy
📦 Storage Conditions
📌 Store in a cool, dry place below 25°C
📌 Keep out of reach of children
🏆 Conclusion
Minoclav-LB 625 Tablets (Amoxycillin 500 mg + Clavulanic Acid 125 mg + Lactic Acid Bacillus 60 Million Spores) is a powerful, broad-spectrum antibiotic with added probiotic protection. It ensures effective infection control while preventing antibiotic-associated gut issues.
✅ Trusted Pharmaceutical Company in India
Since 2007, we have been at the forefront of scientific research and development, consistently delivering breakthrough medicines and therapies that address critical medical challenges. Our experienced team of experts works tirelessly to ensure that our products meet the highest standards of efficacy, safety, and compliance.
🚀 Minoclav-LB 625 – Triple Action Formula for Infection Control & Gut Protection! 💊💪
📞 Contact Us
📞 Phone: +91-9845329972
📧 Email: info@minovalifesciences.com
🌐 Website: Minova Life Sciences
