🔬 Introduction
Minoclav 625 Tablets is a broad-spectrum antibiotic that combines Amoxycillin, a beta-lactam antibiotic, with Clavulanic Acid, a beta-lactamase inhibitor. This powerful combination ensures effective treatment against antibiotic-resistant bacterial infections in the respiratory, urinary, and gastrointestinal tracts.
⚕️ Pharmacokinetics & Bioavailability
✔ Absorption: Rapidly absorbed from the gastrointestinal tract
✔ Bioavailability: Amoxycillin (~75%), Clavulanic Acid (~60%)
✔ Peak Plasma Concentration: 1–2 hours after administration
✔ Protein Binding: Amoxycillin (~18%), Clavulanic Acid (~25%)
✔ Half-life: Amoxycillin (~1–1.5 hours), Clavulanic Acid (~1 hour)
✔ Excretion: Primarily in urine (~70% within 6 hours)
🦠 Indications & Uses
🚑 Minoclav 625 Tablets is prescribed for:
✔ Respiratory Tract Infections (Bronchitis, Pneumonia, Tonsillitis, Sinusitis)
✔ Urinary Tract Infections (UTI) (Cystitis, Pyelonephritis)
✔ Skin & Soft Tissue Infections (Cellulitis, Wound Infections)
✔ Dental Infections (Abscesses, Periodontitis)
✔ Ear Infections (Otitis Media)
✔ Bone & Joint Infections
💊 Dosage & Administration
✔ Adults & Adolescents (>12 years): One tablet every 8-12 hours (as per physician’s guidance)
✔ Children (<12 years): Prefer pediatric suspension or as directed by a doctor
📌 How to take:
- Swallow the tablet whole with water.
- Take with or after food to reduce stomach discomfort.
⚙️ Mechanism of Action
✔ Amoxycillin: Inhibits bacterial cell wall synthesis, leading to bacterial death (bactericidal action)
✔ Clavulanic Acid: Prevents bacterial resistance by inhibiting beta-lactamase enzymes
✔ Effective Against: Streptococcus, Staphylococcus (non-MRSA), Haemophilus influenzae, Escherichia coli, Klebsiella, Proteus, Bacteroides
⚠️ Warnings & Precautions
❌ Penicillin Allergy: Avoid in patients with known hypersensitivity
❌ Liver Impairment: Use with caution in patients with hepatic disorders
❌ Kidney Impairment: Dose adjustment required in severe renal disease
❌ Clostridium difficile Infection: Risk of antibiotic-associated diarrhea
❌ Superinfection Risk: Prolonged use may lead to fungal or resistant bacterial infections
🚨 Adverse Effects
✔ Common: Nausea, vomiting, diarrhea, abdominal pain, skin rash
✔ Serious: Allergic reactions, liver enzyme elevation, Clostridium difficile infection
⚡ Drug Interactions
⚡ Allopurinol: Increases risk of skin rashes
⚡ Warfarin & Anticoagulants: May increase bleeding risk
⚡ Methotrexate: Increases toxicity risk
⚡ Probenecid: Delays amoxycillin excretion, prolonging its effect
⚡ Live Vaccines (e.g., Typhoid Vaccine): May reduce vaccine efficacy
📦 Storage Conditions
📌 Store in a cool, dry place below 25°C
📌 Keep out of reach of children
🏆 Conclusion
Minoclav 625 Tablets (Amoxycillin 500 mg + Clavulanic Acid 125 mg) is a powerful, broad-spectrum antibiotic designed to combat bacterial infections effectively. Its enhanced formulation provides greater protection against resistant bacteria.
✅ Trusted Pharmaceutical Company in India
Since 2007, we have been at the forefront of scientific research and development, consistently delivering breakthrough medicines and therapies that address critical medical challenges. Our experienced team of experts works tirelessly to ensure that our products meet the highest standards of efficacy, safety, and compliance.
🚀 Minoclav 625 – Enhanced Protection Against Resistant Bacteria! 💊💪
📞 Contact Us
📞 Phone: +91-9845329972
📧 Email: info@minovalifesciences.com
🌐 Website: Minova Life Sciences
