Co: Clarithromycin 250mg / 500mg
Also Available:
Claritrac Dry Syrup – Clarithromycin 125mg
🔬 Introduction
Claritrac-250 and 500 Tablets are macrolide antibiotics that contain Clarithromycin, used to treat a wide range of bacterial infections. Known for its broad-spectrum action, it works by inhibiting bacterial protein synthesis. These tablets are highly effective in respiratory tract, skin, ENT, and gastrointestinal infections.
The syrup formulation, Claritrac Dry Syrup (Clarithromycin 125mg), is ideal for pediatric patients.
⚕️ Pharmacokinetics & Bioavailability
✔ Absorption: Rapid from the gastrointestinal tract
✔ Bioavailability: ~50%, increased when taken with food
✔ Peak Plasma Time: 2–3 hours
✔ Protein Binding: ~70%
✔ Half-life: 3–4 hours (prolonged in renal issues)
✔ Metabolism: Liver (CYP3A system)
✔ Excretion: Via urine & bile
🦠 Indications & Uses
Claritrac is effective against a wide variety of pathogens:
Respiratory Tract Infections – Pneumonia, sinusitis, bronchitis
ENT Infections – Tonsillitis, otitis media, pharyngitis
Skin & Soft Tissue Infections – Cellulitis, impetigo
Helicobacter pylori Infection – As part of triple therapy
Atypical Mycobacterial Infections – MAC (Mycobacterium avium complex)
💊 Dosage & Administration
🔹 Adults & Adolescents (>12 years):
Standard: 250 mg or 500 mg twice daily for 7–14 days
Severe infections: 500 mg twice daily
🔹 Pediatric Patients:
Dry Syrup (125 mg/5ml): 7.5 mg/kg twice daily (Max 500 mg/day)
🔹 H. pylori Therapy:
Clarithromycin 500 mg + Amoxicillin 1 g + Omeprazole 20 mg
(Twice daily for 14 days)
📌 Can be taken with or without food (food improves absorption)
⚙️ Mechanism of Action
Inhibits bacterial protein synthesis by binding to 50S ribosomal subunit
Bacteriostatic in action
Effective against: Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, Mycobacterium, H. pylori
⚠️ Warnings & Precautions
❗ Use cautiously in:
Patients with liver disease
Those with a history of QT prolongation or heart rhythm issues
Individuals with myasthenia gravis
Patients with renal impairment
🚨 Adverse Effects
✔ Common:
Nausea, vomiting, diarrhea
Headache, metallic taste
✔ Rare but Serious:
Liver dysfunction
QT prolongation
Allergic reactions
C. difficile-associated diarrhea
⚡ Drug Interactions
⚠ Claritrac interacts with multiple drugs:
Warfarin – Increased bleeding risk
Statins – Risk of muscle breakdown (rhabdomyolysis)
Benzodiazepines – Enhanced sedation
Digoxin – Risk of toxicity
Antiepileptics – May alter serum levels
📦 Storage Conditions
✔ Store below 25°C in a cool, dry place
✔ Protect from light and moisture
✔ Keep out of reach of children
📋 Product Variants
Claritrac-250 Tablet – Clarithromycin 250 mg
Claritrac-500 Tablet – Clarithromycin 500 mg
Claritrac Dry Syrup – Clarithromycin 125 mg/5ml (60 ml pack)
This range ensures complete coverage for adult and pediatric needs in bacterial infection management.
🧠💡 Conclusion
Claritrac Tablets and Syrup deliver powerful, broad-spectrum antibacterial coverage with Clarithromycin, trusted for respiratory, ENT, skin, and GI infections. Its well-documented safety profile and effective dosing make it a go-to macrolide antibiotic for doctors and healthcare professionals.
Since 2007, we have been at the forefront of scientific research and development, consistently delivering breakthrough medicines and therapies that address critical medical challenges. Our experienced team of experts works tirelessly to ensure that our products meet the highest standards of efficacy, safety, and compliance.
Partner with our pharma franchise and join us in shaping the future of healthcare.
📞 Contact Us
📞 Phone: +91-9845329972
📧 Email: info@minovalifesciences.com
🌐 Website: Minova Life Sciences
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