🔬 Introduction
Claritrac Dry Syrup is a macrolide antibiotic formulated for pediatric use to treat bacterial infections in children. It works by inhibiting bacterial protein synthesis, stopping bacterial growth and spread. The pleasant taste makes it easier for children to take, ensuring better compliance and effectiveness.
⚕️ Pharmacokinetics & Bioavailability
✔ Absorption: Rapidly absorbed from the gastrointestinal tract
✔ Bioavailability: ~50% (food enhances absorption)
✔ Peak Plasma Concentration: 2–3 hours after administration
✔ Protein Binding: ~70%
✔ Half-life: ~3–4 hours (longer in renal impairment)
✔ Metabolism: Extensively metabolized in the liver
✔ Excretion: Primarily in urine & bile
🦠 Indications & Uses
🚑 Claritrac Dry Syrup is prescribed for treating:
✔ Upper & Lower Respiratory Tract Infections (Tonsillitis, Pharyngitis, Sinusitis, Pneumonia, Bronchitis)
✔ Otitis Media (Middle Ear Infection)
✔ Skin & Soft Tissue Infections (Impetigo, Cellulitis)
✔ Helicobacter pylori Eradication (As part of triple therapy for pediatric peptic ulcers)
✔ Mycobacterial Infections (Used in HIV-infected children for Mycobacterium avium complex – MAC)
💊 Dosage & Administration
Children (Based on Body Weight):
✔ Standard Dose: 7.5 mg/kg twice daily for 7–14 days
Weight | Dose (Twice Daily) |
5-9 kg | 2.5 mL |
10-19 kg | 5 mL |
20-29 kg | 7.5 mL |
30-40 kg | 10 mL |
✔ H. pylori Eradication: 7.5 mg/kg twice daily for 14 days (as part of combination therapy)
📌 Administration: Shake well before use. Can be taken with or without food (food improves absorption).
⚙️ Mechanism of Action
✔ Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit
✔ Bacteriostatic action (Prevents bacterial growth)
✔ Effective Against: Streptococcus, Staphylococcus, Haemophilus, H. pylori, Mycobacterium
⚠️ Warnings & Precautions
❌ Liver Disease: Use with caution in hepatic impairment
❌ QT Prolongation: Avoid in children with heart rhythm disorders
❌ Renal Impairment: Dose adjustment required in severe cases
❌ Myasthenia Gravis: May worsen symptoms
🚨 Adverse Effects
✔ Common: Nausea, vomiting, diarrhea, headache, altered taste
✔ Serious: Liver toxicity, allergic reactions, irregular heartbeat, Clostridium difficile infection
⚡ Drug Interactions
⚡ Warfarin & Anticoagulants: Increased bleeding risk
⚡ Statins (e.g., Simvastatin, Atorvastatin): Risk of rhabdomyolysis
⚡ Benzodiazepines (e.g., Midazolam): Increased sedative effects
⚡ Antiepileptics (e.g., Phenytoin, Carbamazepine): May increase drug levels
⚡ Digoxin: Risk of toxicity
📦 Storage Conditions
📌 Store in a cool, dry place below 25°C
📌 After reconstitution, use within 7 days (keep refrigerated for best results)
📌 Keep out of reach of children
🏆 Conclusion
Claritrac Dry Syrup (Clarithromycin 125 mg/5 mL) is a safe and effective antibiotic for treating bacterial infections in children. With broad-spectrum action and excellent taste, it ensures better compliance and recovery.
✅ Trusted Pharmaceutical Company in India
Since 2007, we have been at the forefront of scientific research and development, consistently delivering breakthrough medicines and therapies that address critical medical challenges. Our experienced team of experts works tirelessly to ensure that our products meet the highest standards of efficacy, safety, and compliance.
🚀 Claritrac Dry Syrup – Effective Antibiotic for Pediatric Bacterial Infections! 💪
📞 Contact Us
📞 Phone: +91-9845329972
📧 Email: info@minovalifesciences.com
🌐 Website: Minova Life Sciences
